产品货号：
Z19058
中文名称：
HSF2抗体
英文名称：
Anti-HSF2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HSF2 Antibody |
| 指标别名 | Heat shock factor protein 2;HSF 2;HSF2;HSTF 2;HSTF2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | HSF2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human HSF2(82-102aa KQERDGPVEFQHPYFKQGQDD),identical to the related mouse sequence,and different from the related rat sequence by one amino acid. |
| 实际分子量 | 60KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HSF2(HEAT-SHOCK TRANSCRIPTION FACTOR 2),also called HEAT-SHOCK FACTOR 2,as well as the related gene HSF1,encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species.The International Radiation Hybrid Mapping Consortium maps the HSF2 gene to chromosome 6.Mouse Hsf2 was expressed in all 3 embryonic layers at embryonic day 7.5 and that the head fold was strongly stained at embryonic day 8.5.In adults,Hsf2 expression is detected in spermatocytes and spermatogonia,but not in elongated spermatids,spermatozoa,or Sertoli cells.Hsp70i bookmarking is mediated by a transcription factor called HSF2,which binds this promoter in mitotic cells,recruits protein phosphatase-2A,and interacts with the CAPG subunit of the condensin enzyme to promote efficient dephosphorylation and inactivation of condensin complexes in the vicinity,thereby preventing compaction at this site.And Hsf2-null mice were born at the expected mendelian ratio but had brain abnormalities and meiotic and gametogenic defects in both genders. |
| Uniprot ID | Q03933 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | heat shock transcription factor 2 |
| 蛋白名全称 | Heat shock factor protein 2(HSF 2) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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